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Semaglutide: Frequently Asked Questions

What is Semaglutide?

Semaglutide, also known by its brand name Wegovy, is a medication that has been approved by the FDA for chronic weight management. It belongs to a class of drugs called glucagon-like peptide-1 (GLP-1) receptor agonists, which are typically used to treat type 2 diabetes.

How Does Semaglutide work?

Semaglutide has been shown to help people lose weight by suppressing appetite and reducing food intake. Clinical trials have demonstrated that patients who take Semaglutide in combination with a healthy diet and exercise can achieve significant weight loss compared to those who use a placebo.

GLP-1 receptor agonists, such as Semaglutide, work by mimicking the effects of GLP-1 in the body. By activating GLP-1 receptors, these medications can help to stimulate insulin secretion, reduce appetite, and slow down gastric emptying, which can lead to weight loss and improved blood sugar control.

Who is right for Semaglutide?

In addition to being approved for chronic weight management in adults, Semaglutide is also FDA-approved for use in adolescents aged 12 years and older who have a body mass index (BMI) at or above the 95th percentile for their age and sex.

As with adults, Semaglutide should be used in combination with lifestyle changes, including a healthy diet and exercise, in adolescents. A healthcare provider can help determine if Semaglutide is a suitable treatment option and develop a plan to help adolescents achieve their weight loss goals while ensuring that their nutritional needs are met during a critical period of growth and development.

How long do I have to be on Semaglutide?

The dosing regimen is designed to gradually increase the dose of Semaglutide over a period of four months, with the aim of reaching a target maintenance dose of 2.4 mg once weekly.

The recommended dosing regimen is as follows:

  • Month 1: 0.25 mg once weekly for the first month

  • Month 2: 0.5 mg once weekly for the second month

  • Month 3: 1 mg once weekly for the third month

  • Month 4: 1.7 mg once weekly for the fourth month

  • Target maintenance dose: 2.4 mg once weekly


It's important to note that this dosing regimen may be adjusted based on individual response and tolerability. A healthcare provider can help determine the appropriate dosing regimen for each patient and monitor their progress while using Semaglutide.

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